EPITHALON PEPTIDE
EPITHALON PEPTIDE
Epitalon (Epithalon) dosage protocols center on this synthetic tetrapeptide (Ala-Glu-Asp-Gly) developed from pineal gland research for its geroprotective potential[1]. Epitalon activates telomerase to promote telomere elongation, supports healthy melatonin production for improved sleep and circadian rhythm regulation, and has demonstrated lifespan extension in animal models[2][3]. Human studies suggest potential benefits for longevity, cardiovascular health, and physiological function in older adults[4]. This educational protocol presents a once-daily subcutaneous approach using a practical dilution for clear insulin-syringe measurements.
- Reconstitute: Add 2.0 mL bacteriostatic water → 5 mg/mL concentration.
- Typical daily dose: 5,000 mcg (5 mg) once daily for 20 consecutive days.
- Easy measuring: At 5 mg/mL, 1 unit = 0.01 mL = 50 mcg on a U-100 insulin syringe.
- Storage: Lyophilized: freeze at −20 °C (−4 °F); after reconstitution, refrigerate at 2–8 °C (35.6–46.4 °F); avoid freeze–thaw cycles.
Standard Protocol (2 mL = 5 mg/mL)
| Phase | Daily Dose (mcg) | Units (per injection) (mL) |
|---|---|---|
| Days 1–20 (Cycle On) | 5,000 mcg (5 mg) | 100 units (1.00 mL) |
| Weeks 4–26 (Cycle Off) | 0 mcg | — |
Frequency: Inject once daily subcutaneously, preferably in the evening or at bedtime to synergize with natural melatonin rhythms[3]. Complete 20 consecutive days, then observe a 4–6 month off-cycle before repeating (typically 2 cycles per year)[5].
Reconstitution Steps
- Draw 2.0 mL bacteriostatic water with a sterile syringe.
- Inject slowly down the vial wall; avoid foaming.
- Gently swirl/roll until dissolved (do not shake).
- Label and refrigerate at 2–8 °C (35.6–46.4 °F), protected from light.
